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Gabor Halmos Selected Research

Gastrin-Releasing Peptide

2/2013Shrinkage of experimental benign prostatic hyperplasia and reduction of prostatic cell volume by a gastrin-releasing peptide antagonist.
10/2012Powerful inhibition of in-vivo growth of experimental hepatic cancers by bombesin/gastrin-releasing peptide antagonist RC-3940-II.
11/2007Growth inhibition of non-small-cell lung carcinoma by BN/GRP antagonist is linked with suppression of K-Ras, COX-2, and pAkt.
1/2006Targeted chemotherapy with cytotoxic bombesin analogue AN-215 inhibits growth of experimental human prostate cancers.
12/2005Targeted cytotoxic bombesin analog AN-215 effectively inhibits experimental human breast cancers with a low induction of multi-drug resistance proteins.
10/2005Inhibition of growth of experimental human and hamster pancreatic cancers in vivo by a targeted cytotoxic bombesin analog.
8/2005Antagonists of growth hormone releasing hormone (GHRH) and of bombesin/gastrin releasing peptide (BN/GRP) suppress the expression of VEGF, bFGF, and receptors of the EGF/HER family in PC-3 and DU-145 human androgen-independent prostate cancers.
3/2005Effective inhibition of experimental human ovarian cancers with a targeted cytotoxic bombesin analogue AN-215.
2/2005Antagonists of bombesin/gastrin-releasing peptide decrease the expression of angiogenic and anti-apoptotic factors in human glioblastoma.
1/2005Inhibitory effect of antagonists of bombesin and growth hormone-releasing hormone on orthotopic and intraosseous growth and invasiveness of PC-3 human prostate cancer in nude mice.

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Gabor Halmos Research Topics

Disease

64Neoplasms (Cancer)
04/2022 - 01/2002
16Prostatic Neoplasms (Prostate Cancer)
01/2017 - 02/2002
15Carcinoma (Carcinomatosis)
08/2010 - 02/2002
7Breast Neoplasms (Breast Cancer)
08/2009 - 09/2003
6Endometrial Neoplasms (Endometrial Cancer)
04/2022 - 08/2003
6Lymphoma (Lymphomas)
01/2017 - 10/2004
4Ovarian Neoplasms (Ovarian Cancer)
01/2022 - 03/2005
4Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 02/2002
4Glioblastoma (Glioblastoma Multiforme)
01/2022 - 02/2005
4Neoplasm Metastasis (Metastasis)
01/2020 - 01/2005
4Uveal melanoma
01/2020 - 10/2013
4Pancreatic Neoplasms (Pancreatic Cancer)
05/2013 - 10/2005
4Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
02/2013 - 03/2011
3Renal Cell Carcinoma (Grawitz Tumor)
01/2017 - 08/2005
3Adenocarcinoma
01/2017 - 10/2002
3Melanoma (Melanoma, Malignant)
10/2013 - 07/2005
3Liver Neoplasms (Liver Cancer)
10/2012 - 02/2005
3Lung Neoplasms (Lung Cancer)
10/2011 - 11/2005
3Colonic Neoplasms (Colon Cancer)
10/2009 - 02/2002
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2006 - 05/2003
2Hepatocellular Carcinoma (Hepatoma)
04/2008 - 02/2005
2Small Cell Lung Carcinoma (Small Cell Lung Cancer)
11/2007 - 08/2005
2Glioma (Gliomas)
07/2005 - 02/2005
2Body Weight (Weight, Body)
05/2005 - 04/2005
1Hodgkin Disease (Hodgkin's Disease)
12/2020
1Chromosome Aberrations (Chromosome Abnormalities)
04/2017
1Myocardial Infarction
02/2014
1Gynatresia
01/2014
1Hypoxia (Hypoxemia)
01/2014
1Urinary Bladder Neoplasms (Bladder Cancer)
07/2012
1Lower Urinary Tract Symptoms
04/2011
1Leukemia
08/2010

Drug/Important Bio-Agent (IBA)

28Messenger RNA (mRNA)IBA
04/2022 - 02/2002
23Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA
04/2022 - 01/2002
20Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2020 - 09/2003
16Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
12/2020 - 02/2002
16BombesinIBA
10/2012 - 10/2003
16AN 204 (AN 201)IBA
06/2007 - 02/2002
15Proteins (Proteins, Gene)FDA Link
01/2018 - 04/2005
13LigandsIBA
04/2022 - 10/2002
12Doxorubicin (Adriamycin)FDA LinkGeneric
05/2013 - 04/2003
11LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA
01/2020 - 09/2003
11AndrogensIBA
04/2012 - 02/2002
11AN 238IBA
07/2006 - 02/2002
10Somatostatin Receptors (Somatostatin Receptor)IBA
06/2018 - 02/2002
10Gastrin-Releasing PeptideIBA
02/2013 - 01/2005
9AN 215IBA
07/2006 - 10/2003
8somatotropin releasing hormone receptorIBA
01/2017 - 06/2002
8Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2012 - 02/2005
7lysine(6)-doxorubicin LHRHIBA
01/2020 - 09/2003
7RC 121IBA
08/2010 - 02/2002
7AN 207IBA
06/2007 - 04/2005
5Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
02/2013 - 08/2005
5MZ-J-7-138IBA
04/2012 - 07/2005
5Insulin-Like Growth Factor I (IGF-1)IBA
03/2006 - 04/2002
4Hca(6)-Leu(13)-psi(CH2N)-Tac(14)- bombesin(6-14)IBA
10/2012 - 01/2005
4cetrorelix (Cetrotide)FDA Link
04/2012 - 09/2007
4Peptides (Polypeptides)IBA
03/2011 - 07/2006
4Insulin-Like Growth Factor II (Somatomedin A)IBA
12/2008 - 11/2003
4MZ-J-7-118IBA
09/2007 - 01/2005
4Protein Isoforms (Isoforms)IBA
08/2006 - 06/2002
3Har(29)- Arg(28) Nle(27) Orn(21) His(20) Orn(12,) Abu(15) His(11) Tyr(Me)(10) Har(9) Ala(8) Fpa(5,6) Arg(2) (PhAc-Ada)(0)-Tyr(1) GHRH(1-29)NH2IBA
01/2022 - 02/2012
3Hormones (Hormone)IBA
01/2018 - 10/2004
3Epidermal Growth Factor (EGF)IBA
09/2007 - 08/2005
3RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
06/2007 - 10/2003
3ErbB Receptors (EGF Receptor)IBA
02/2007 - 10/2003
3JV 1-38IBA
08/2006 - 11/2003
2Antineoplastic Agents (Antineoplastics)IBA
01/2022 - 10/2005
2Human Growth Hormone (Saizen)FDA LinkGeneric
01/2017 - 10/2004
2Vasoactive Intestinal Peptide Receptors (Vasoactive Intestinal Peptide Receptor)IBA
10/2011 - 04/2002
2PhAcTyr(1)- Arg(2)- P(H)e(4- CL)(6)- Ala(8)- Tyr(Me)(10)- His(11)- Abu(15)- His(20)- Nle(27)- Arg(28)- HLCr(29)- GHRH(1-29)NH2IBA
10/2009 - 02/2007
2Estrogens (Estrogen)FDA Link
08/2009 - 09/2003
2Docetaxel (Taxotere)FDA Link
02/2007 - 09/2006
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
07/2006 - 11/2005
2Membrane Transport Proteins (Biological Pump)IBA
11/2005 - 09/2005
2Triptorelin Pamoate (Trelstar)FDA Link
08/2005 - 10/2003
2Insulin-Like PeptidesIBA
02/2004 - 11/2003
2vapreotideIBA
05/2003 - 04/2002
2pentetreotide (OctreoScan)FDA Link
05/2003 - 04/2003
2Membrane Proteins (Integral Membrane Proteins)IBA
10/2002 - 06/2002
1NeuropeptidesIBA
12/2020
1Hypothalamic HormonesIBA
01/2018
1MR 356IBA
02/2014
1N-Me-Tyr1,D-Ala2,Asn8,Arg29-NHCH3-JI-38IBA
02/2014
1JI-38IBA
02/2014
1Gonadal Steroid Hormones (Sex Hormones)IBA
05/2013
1matrigelIBA
02/2012
1EnzymesIBA
02/2012
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
02/2012
1ImmunosorbentsIBA
02/2012
1Type I Vasoactive Intestinal Polypeptide ReceptorsIBA
10/2011
1Type II Vasoactive Intestinal Peptide ReceptorsIBA
10/2011
1CytokinesIBA
05/2011
1glutaric acidIBA
08/2009

Therapy/Procedure

32Therapeutics
01/2022 - 01/2002
20Drug Therapy (Chemotherapy)
08/2009 - 02/2002
3Aftercare (After-Treatment)
07/2006 - 02/2005
3Injections
09/2003 - 02/2002
2Investigational Therapies (Experimental Therapy)
06/2007 - 08/2005
1Uterine Myomectomy
01/2014